Image provided by Chris Boyle, Specsavers
Congenital cataracts are a common major abnormality of the eye that frequently cause blindness in infants.
At least a third of all cases are familial; autosomal dominant congenital cataract (ADCC) appears to be the most common familial form in the Western world. Cerulean cataracts may be caused by mutations in several genes, including the CRYBB2, CRYGD, and MAF genes.
Cerulean cataracts have peripheral bluish and white opacification in concentric layers with occasional central lesions arranged radially.
Although the opacities may be observed during fetal development and childhood, usually visual acuity is only mildly reduced until adulthood, when lens extraction is generally necessary.
Share, Print or Favourite